Playground · No signup

Try NOVA-3 in your browser.

Pick what you want to do — design candidates for a target, fold a sequence, or verify an Evidence Bundle on Bitcoin. All three call the real NOVA-3 backend.

Design candidates

Target Modality Affinity goal (pM)

Try a preset

CLDN18.2 · TCE GD3 · senolytic TfR1 · shuttle HER2 · ADC

Design output Idle

Pick a target. Press run.

NOVA-3 will search the Module Library, generate multi-specific combinations, rank by predicted Kd, and anchor the result to Bitcoin.

Fold sequence

Amino-acid sequence (single chain, ≤ 400 aa)

Preset sequences

VHH (P2 shuttle) scFv (P1 CD3) P3 lead binder Ubiquitin (sanity)

Mol* · ESMFold result Idle

Paste a sequence. Get a structure.

Real ESMFold call via the NOVA-3 backend. Mol* renders the structure with pLDDT confidence colouring. 5–30 seconds.

Verify Evidence Bundle

Bundle ID

Demo bundles

P3 GD3 lead P1 CLDN18.2 P2 TfR1 shuttle Flagship demo

OpenTimestamps verification Idle

Anyone can verify. No login.

Every result NOVA-3 produces is anchored as a SHA-256 root committed to Bitcoin via OpenTimestamps. Paste a bundle ID — we re-check against the public chain.